SSRP1

UniProt Accession Q08945 UniProt 🔗
Synonyms FACT80
UniProt protein names FACT complex subunit SSRP1;
Chromatin-specific transcription elongation factor 80 kDa subunit;
Facilitates chromatin transcription complex 80 kDa subunit;
Facilitates chromatin transcription complex subunit SSRP1;
Recombination signal sequence recognition protein 1;
Structure-specific recognition protein 1;
T160
Peak binding time (min) 0.0
Cluster I
Cluster membership (corr) 0.997
Peak broadness (1 / std of log2 intensities) 1.08
Cluster expected from GO II
Subcellular localization (Human Protein Atlas) Cytosol;Nucleus
Subcellular localization (Human Cell Map) NMF result: chromatin, SAFE result: chromatin, nucleoplasm
RMSE (expected - observed) 0.24
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics

Gene Ontology based expectation (GO 2021-09-01)

Protein interactors of SSRP1 in mRNP (BioGRID)

Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
Q9Y5B9 SUPT16H 12.0 I Nucleoli fibrillar center;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 6 12
P09429 HMGB1 49.8 III Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 2 3
Q86VM9 ZC3H18 39.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 2
O14646 CHD1 42.9 II Nucleoli fibrillar center;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 2 2
P33992 MCM5 42.8 III Nucleoplasm NMF result: no prediction, SAFE result: no prediction 2 2
P12956 XRCC6 47.9 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 2 2
Q96QD9 FYTTD1 75.0 V Nuclear speckles NMF result: no prediction, SAFE result: no prediction 2 1
Q92541 RTF1 40.9 II Cytosol;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 2
O00422 SAP18 63.4 IV Cytosol;Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 2
Q96SB4 SRPK1 52.0 IV Cytosol;Nucleus;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P11388 TOP2A 49.6 III Nucleoli;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P24928 POLR2A 0.0 I Nucleoplasm NMF result: miscellaneous, SAFE result: chromatin, nucleoplasm 1 1
Q7KZ85 SUPT6H 0.0 I Cytosol;Nucleoplasm;Plasma membrane NMF result: miscellaneous, SAFE result: chromatin, nucleoplasm 1 1
Q96PK6 RBM14 42.9 II Nuclear speckles NMF result: nuclear body, SAFE result: paraspeckles 1 1
P46087 NOP2 57.6 IV Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q8TAD8 SNIP1 40.9 II Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
P09874 PARP1 45.3 II Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q9Y2W1 THRAP3 37.2 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O75534 CSDE1 122.4 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q08211 DHX9 50.2 III Nucleus NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q4G0J3 LARP7 54.3 IV Cytosol;Nucleoplasm NMF result: nucleolus, SAFE result: paraspeckles 1 1
P62820 RAB1A 45.1 III Cytosol;Endoplasmic reticulum NMF result: mitochondrial outer membrane, peroxisome, SAFE result: no prediction 1 1
Q15029 EFTUD2 45.5 III Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: spliceosomal complex I 1 1
O15347 HMGB3 46.3 III Nucleoli;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q01780 EXOSC10 58.1 IV Cytosol;Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q9UKV3 ACIN1 60.5 IV Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O75533 SF3B1 40.9 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q14839 CHD4 61.8 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q12873 CHD3 52.4 IV Microtubule organizing center;Nucleoli;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1