NUDT21

UniProt Accession O43809 UniProt 🔗
Synonyms CFIM25, CPSF25, CPSF5
UniProt protein names Cleavage and polyadenylation specificity factor subunit 5;
Cleavage and polyadenylation specificity factor 25 kDa subunit;
Cleavage factor Im complex 25 kDa subunit;
Nucleoside diphosphate-linked moiety X motif 21;
Nudix hydrolase 21;
Pre-mRNA cleavage factor Im 68 kDa subunit
Peak binding time (min) 41.6
Cluster II
Cluster membership (corr) 1.000
Peak broadness (1 / std of log2 intensities) 0.89
Cluster expected from GO I
Subcellular localization (Human Protein Atlas) Nuclear bodies
Subcellular localization (Human Cell Map) NMF result: nuclear body, SAFE result: splicing speckles, nucleolus
RMSE (expected - observed) 0.31
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics

Gene Ontology based expectation (GO 2021-09-01)

Protein interactors of NUDT21 in mRNP (BioGRID)

Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
Q16630 CPSF6 33.9 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 3 6
Q8N684 CPSF7 36.9 II Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 3 5
P08621 SNRNP70 32.2 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 2 2
Q69YN4 VIRMA 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 1
Q15287 RNPS1 58.0 IV Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 2
O14776 TCERG1 40.9 II Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P42285 MTREX 73.4 V Nucleus NMF result: chromatin, SAFE result: - 1 1
Q96SB4 SRPK1 52.0 IV Cytosol;Nucleus;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P27694 RPA1 45.5 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q13523 PRPF4B 45.4 III Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q14152 EIF3A 198.2 VII Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q5TC82 RC3H1 62.0 IV Cytosol;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q92879 CELF1 49.2 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P12956 XRCC6 47.9 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
O95985 TOP3B 72.2 V Vesicles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q15717 ELAVL1 46.3 III Cytosol;Nucleoli;Nucleus NMF result: miscellaneous, SAFE result: paraspeckles 1 1
P06748 NPM1 56.1 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q99459 CDC5L 49.2 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P35637 FUS 37.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q13595 TRA2A 42.2 II Nucleoli;Vesicles NMF result: no prediction, SAFE result: no prediction 1 1
P51116 FXR2 171.1 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q12986 NFX1 77.5 V Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P09651 HNRNPA1 43.1 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
B5ME19 EIF3CL 170.8 VII Cytosol NMF result: miscellaneous, SAFE result: - 1 1
Q15029 EFTUD2 45.5 III Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: spliceosomal complex I 1 1
Q8WXF1 PSPC1 44.9 II Nucleoli fibrillar center;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q86VM9 ZC3H18 39.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O75533 SF3B1 40.9 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q15056 EIF4H 115.6 VI Cytosol;Nuclear bodies;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: - 1 1