PTBP2
| UniProt Accession | Q9UKA9 UniProt 🔗 |
|---|---|
| Synonyms | NPTB, PTB, PTBLP |
| UniProt protein names | Polypyrimidine tract-binding protein 2;Neural polypyrimidine tract-binding protein;Neurally-enriched homolog of PTB;PTB-like protein |
| Peak binding time (min) | 44.3 |
| Cluster | II |
| Cluster membership (corr) | 0.998 |
| Peak broadness (1 / std of log2 intensities) | 0.93 |
| Cluster expected from GO | III |
| Subcellular localization (Human Protein Atlas) | Nucleoplasm |
| Subcellular localization (Human Cell Map) | NMF result: nuclear body, SAFE result: paraspeckles |
| RMSE (expected - observed) | 0.23 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of PTBP2 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| Q15717 | ELAVL1 | 46.3 | III | Cytosol;Nucleoli;Nucleus | NMF result: miscellaneous, SAFE result: paraspeckles | 3 | 3 |
| P43243 | MATR3 | 47.9 | III | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 3 | |
| P98175 | RBM10 | 33.0 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 3 |
| Q96PU8 | QKI | 47.1 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 2 |
| P09012 | SNRPA | 44.9 | III | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 2 |
| Q92945 | KHSRP | 37.0 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P07910 | HNRNPC | 47.9 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q07666 | KHDRBS1 | 43.0 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P14866 | HNRNPL | 42.6 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q14103 | HNRNPD | 43.1 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q99459 | CDC5L | 49.2 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q99729 | HNRNPAB | 42.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q9UHX1 | PUF60 | 35.4 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q92879 | CELF1 | 49.2 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P35637 | FUS | 37.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q9BWF3 | RBM4 | 40.3 | II | Cytosol;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |