SRSF10

UniProt Accession O75494 UniProt 🔗
Synonyms FUSIP1, FUSIP2, SFRS13A, TASR
UniProt protein names Serine/arginine-rich splicing factor 10;
40 kDa SR-repressor protein;
FUS-interacting serine-arginine-rich protein 1;
Splicing factor SRp38;
Splicing factor, arginine/serine-rich 13A;
TLS-associated protein with Ser-Arg repeats;
TLS-associated serine-arginine protein
Peak binding time (min) 46.3
Cluster II
Cluster membership (corr) 0.997
Peak broadness (1 / std of log2 intensities) 0.99
Cluster expected from GO II
Subcellular localization (Human Protein Atlas) Nucleoplasm
Subcellular localization (Human Cell Map) NMF result: nuclear body, SAFE result: chromatin, nucleoplasm
RMSE (expected - observed) 0.18
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics

Gene Ontology based expectation (GO 2021-09-01)

Protein interactors of SRSF10 in mRNP (BioGRID)

Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
Q13595 TRA2A 42.2 II Nucleoli;Vesicles NMF result: no prediction, SAFE result: no prediction 2 3
P49761 CLK3 52.9 III Intermediate filaments;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 2 2
P26368 U2AF2 37.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: - 2 2
P38919 EIF4A3 67.1 V Nucleoplasm NMF result: no prediction, SAFE result: no prediction 2 2
P35637 FUS 37.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 1
Q8TAD8 SNIP1 40.9 II Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 2
P08621 SNRNP70 32.2 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 2
Q86VM9 ZC3H18 39.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 2
Q9NQ29 LUC7L 43.6 II Mitochondria;Nucleus NMF result: no prediction, SAFE result: no prediction 1 2
Q9Y383 LUC7L2 29.7 II Nucleus NMF result: ER lumen, SAFE result: - 1 2
Q08170 SRSF4 44.0 II Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q9H307 PNN 64.6 IV Nuclear speckles NMF result: nuclear body, SAFE result: spliceosomal complex II 1 1
Q13247 SRSF6 45.9 II Nuclear speckles NMF result: nuclear body, SAFE result: spliceosomal complex II 1 1
O14776 TCERG1 40.9 II Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q5TC82 RC3H1 62.0 IV Cytosol;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P07814 EPRS 29.5 II Cytosol NMF result: actin cytoskeleton, cytosol, SAFE result: cell junction, plasma membrane 1 1
O00422 SAP18 63.4 IV Cytosol;Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q96PK6 RBM14 42.9 II Nuclear speckles NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q14103 HNRNPD 43.1 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q07955 SRSF1 41.6 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q15287 RNPS1 58.0 IV Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P61326 MAGOH 70.2 V Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P09429 HMGB1 49.8 III Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q13123 IK 51.9 IV Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q13428 TCOF1 0.0 I Nucleoli fibrillar center NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
O43143 DHX15 35.8 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
P62995 TRA2B 42.0 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1