RRP8

UniProt Accession O43159 UniProt 🔗
Synonyms KIAA0409, NML, hucep-1
UniProt protein names Ribosomal RNA-processing protein 8;
Cerebral protein 1;
Nucleomethylin
Peak binding time (min) 43.2
Cluster II
Cluster membership (corr) 0.998
Peak broadness (1 / std of log2 intensities) 0.92
Cluster expected from GO IV
Subcellular localization (Human Protein Atlas) Cytosol;Nucleoli;Nucleus
Subcellular localization (Human Cell Map) NMF result: nucleolus, SAFE result: splicing speckles, nucleolus
RMSE (expected - observed) 0.31
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics

Gene Ontology based expectation (GO 2021-09-01)

Protein interactors of RRP8 in mRNP (BioGRID)

Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 2 2
Q9BYG3 NIFK 58.9 IV Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 2
Q12905 ILF2 48.0 III Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 2
Q9UGY1 NOL12 73.1 V Nucleoli;Nucleus;Vesicles NMF result: no prediction, SAFE result: no prediction 1 2
P06748 NPM1 56.1 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 2
P42696 RBM34 41.1 II Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q15397 PUM3 58.6 IV Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q5VYS8 TUT7 75.9 V Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9H7B2 RPF2 69.1 V Nucleoli;Nucleus NMF result: miscellaneous, SAFE result: - 1 1
Q9Y2R4 DDX52 52.8 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q9H8H2 DDX31 40.8 II Golgi apparatus;Nucleoli;Vesicles NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q7L2E3 DHX30 56.5 IV Cytosol;Mitochondria NMF result: mitochondrial matrix, SAFE result: mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix 1 1
O60287 URB1 9.2 I Nucleoli fibrillar center NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
P51114 FXR1 172.6 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q9BQ39 DDX50 23.3 II Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
P62633 CNBP 105.4 VI Cytosol;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q5JTH9 RRP12 53.2 III Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q8IY81 FTSJ3 69.4 V Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q6PK04 CCDC137 59.7 V Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
O15381 NVL 49.2 III Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q9H0A0 NAT10 55.7 IV Midbody;Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
P51116 FXR2 171.1 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q8TDD1 DDX54 67.3 V Golgi apparatus;Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
O96028 NSD2 41.7 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q9BZE4 GTPBP4 76.2 V Nuclear membrane;Nucleoli NMF result: nucleolus, SAFE result: no prediction 1 1
Q9UHA3 RSL24D1 62.1 IV Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q9NP64 ZCCHC17 44.4 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q15646 OASL 104.1 VI Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9GZR7 DDX24 58.0 IV Cytosol;Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q2TB10 ZNF800 49.2 III Cytosol;Nucleoli NMF result: no prediction, SAFE result: no prediction 1 1
Q8N8A6 DDX51 25.7 II Cytosol;Nucleoli;Nucleus NMF result: nucleoplasm, SAFE result: - 1 1
Q9BWF3 RBM4 40.3 II Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9GZR2 REXO4 52.4 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q1ED39 KNOP1 38.4 II Cytosol;Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q14146 URB2 5.1 I Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9H7N4 SCAF1 31.3 II Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q13823 GNL2 111.9 VI Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q8N5C6 SRBD1 38.5 III Cytosol;Mitochondria NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q96ME7 ZNF512 45.2 III Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q8TDN6 BRIX1 58.0 IV Nucleoli NMF result: miscellaneous, SAFE result: no prediction 1 1
Q03701 CEBPZ 52.3 III Nucleus;Vesicles NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q96GQ7 DDX27 62.3 IV Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9NZM5 NOP53 89.6 V Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9NW13 RBM28 49.3 III Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P08621 SNRNP70 32.2 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q7Z2W4 ZC3HAV1 211.8 VII Cytosol;Golgi apparatus NMF result: nuclear outer membrane-ER membrane network, SAFE result: nuclear outer membrane-ER membrane network 1 1
Q9BQG0 MYBBP1A 54.4 IV Nucleoli;Vesicles NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1