CSTF2
| UniProt Accession | P33240 UniProt 🔗 |
|---|---|
| Synonyms | |
| UniProt protein names | Cleavage stimulation factor subunit 2;CF-1 64 kDa subunit;Cleavage stimulation factor 64 kDa subunit |
| Peak binding time (min) | 23.7 |
| Cluster | II |
| Cluster membership (corr) | 0.993 |
| Peak broadness (1 / std of log2 intensities) | 0.85 |
| Cluster expected from GO | I |
| Subcellular localization (Human Protein Atlas) | Nuclear bodies;Nucleoplasm |
| Subcellular localization (Human Cell Map) | NMF result: nuclear body, SAFE result: no prediction |
| RMSE (expected - observed) | 0.17 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of CSTF2 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| Q12996 | CSTF3 | 9.6 | I | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 3 | 3 |
| P53999 | SUB1 | 43.3 | II | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 3 | 1 |
| Q92499 | DDX1 | 74.7 | V | Cytosol;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 2 | 2 |
| Q05048 | CSTF1 | 22.4 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 2 | 2 |
| Q9H0L4 | CSTF2T | 14.0 | I | Nucleoplasm | NMF result: actin cytoskeleton, cytosol, SAFE result: no prediction | 2 | 2 |
| P24928 | POLR2A | 0.0 | I | Nucleoplasm | NMF result: miscellaneous, SAFE result: chromatin, nucleoplasm | 2 | 1 |
| P23588 | EIF4B | 213.8 | VII | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 2 |
| Q7Z6E9 | RBBP6 | 43.3 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q01844 | EWSR1 | 36.3 | II | Nucleoli;Nucleus | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q9ULX6 | AKAP8L | 39.8 | II | Nuclear speckles | NMF result: miscellaneous, SAFE result: - | 1 | 1 |
| Q15233 | NONO | 42.9 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q15717 | ELAVL1 | 46.3 | III | Cytosol;Nucleoli;Nucleus | NMF result: miscellaneous, SAFE result: paraspeckles | 1 | 1 |
| P27816 | MAP4 | 62.7 | V | Cytosol;Microtubules;Plasma membrane | NMF result: microtubule cytoskeleton, SAFE result: microtubule cytoskeleton | 1 | 1 |
| Q16630 | CPSF6 | 33.9 | II | Nuclear speckles;Nucleoplasm | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q6UN15 | FIP1L1 | 19.3 | I | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| O95639 | CPSF4 | 36.9 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9HCE1 | MOV10 | 221.0 | VII | Cytosol | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P08621 | SNRNP70 | 32.2 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P11940 | PABPC1 | 124.3 | VI | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q8IYB3 | SRRM1 | 39.4 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q12873 | CHD3 | 52.4 | IV | Microtubule organizing center;Nucleoli;Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |