SETD2
| UniProt Accession | Q9BYW2 UniProt 🔗 |
|---|---|
| Synonyms | HIF1, HSPC069, HYPB, KIAA1732, KMT3A, SET2 |
| UniProt protein names | Histone-lysine N-methyltransferase SETD2;HIF-1;Huntingtin yeast partner B;Huntingtin-interacting protein 1;Huntingtin-interacting protein B;Lysine N-methyltransferase 3A;Protein-lysine N-methyltransferase SETD2;SET domain-containing protein 2;p231HBP |
| Peak binding time (min) | 28.3 |
| Cluster | II |
| Cluster membership (corr) | 0.994 |
| Peak broadness (1 / std of log2 intensities) | 0.99 |
| Cluster expected from GO | II |
| Subcellular localization (Human Protein Atlas) | Cytosol;Nuclear speckles |
| Subcellular localization (Human Cell Map) | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus |
| RMSE (expected - observed) | 0.13 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of SETD2 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| P24928 | POLR2A | 0.0 | I | Nucleoplasm | NMF result: miscellaneous, SAFE result: chromatin, nucleoplasm | 2 | 2 |
| Q8WVV9 | HNRNPLL | 43.8 | II | Cytosol;Mitochondria;Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q15717 | ELAVL1 | 46.3 | III | Cytosol;Nucleoli;Nucleus | NMF result: miscellaneous, SAFE result: paraspeckles | 1 | 1 |
| Q69YN4 | VIRMA | 0.0 | I | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P06748 | NPM1 | 56.1 | IV | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P27694 | RPA1 | 45.5 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9NQ29 | LUC7L | 43.6 | II | Mitochondria;Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |