PABPN1
| UniProt Accession | Q86U42 UniProt 🔗 |
|---|---|
| Synonyms | PAB2, PABP2 |
| UniProt protein names | Polyadenylate-binding protein 2;Nuclear poly(A)-binding protein 1;Poly(A)-binding protein II;Polyadenylate-binding nuclear protein 1 |
| Peak binding time (min) | 44.3 |
| Cluster | II |
| Cluster membership (corr) | 0.996 |
| Peak broadness (1 / std of log2 intensities) | 1.09 |
| Cluster expected from GO | III |
| Subcellular localization (Human Protein Atlas) | |
| Subcellular localization (Human Cell Map) | NMF result: no prediction, SAFE result: no prediction |
| RMSE (expected - observed) | 0.18 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of PABPN1 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| Q13573 | SNW1 | 51.8 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 4 | 2 |
| Q99729 | HNRNPAB | 42.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 3 | 1 |
| P09651 | HNRNPA1 | 43.1 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 3 | 1 |
| P07900 | HSP90AA1 | 48.1 | III | Cytosol | NMF result: no prediction, SAFE result: no prediction | 2 | 1 |
| O95793 | STAU1 | 111.0 | VI | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 2 |
| Q01844 | EWSR1 | 36.3 | II | Nucleoli;Nucleus | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q15717 | ELAVL1 | 46.3 | III | Cytosol;Nucleoli;Nucleus | NMF result: miscellaneous, SAFE result: paraspeckles | 1 | 1 |
| Q5TC82 | RC3H1 | 62.0 | IV | Cytosol;Plasma membrane | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| Q86VM9 | ZC3H18 | 39.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P51532 | SMARCA4 | 51.3 | III | Nucleoplasm | NMF result: nucleoplasm, SAFE result: Arp2/3 protein complex | 1 | 1 |
| P08621 | SNRNP70 | 32.2 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q13148 | TARDBP | 49.3 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P31943 | HNRNPH1 | 40.8 | II | Cytosol;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P04406 | GAPDH | 42.0 | III | Cytosol;Plasma membrane | NMF result: mitochondrial outer membrane, peroxisome, SAFE result: - | 1 | 1 |
| P26368 | U2AF2 | 37.3 | II | Nuclear speckles;Nucleoplasm | NMF result: nuclear body, SAFE result: - | 1 | 1 |
| Q4G0J3 | LARP7 | 54.3 | IV | Cytosol;Nucleoplasm | NMF result: nucleolus, SAFE result: paraspeckles | 1 | 1 |
| P35637 | FUS | 37.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q9NYF8 | BCLAF1 | 37.5 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |