EIF2S3
| UniProt Accession | P41091 UniProt 🔗 |
|---|---|
| Synonyms | EIF2G |
| UniProt protein names | Eukaryotic translation initiation factor 2 subunit 3;Eukaryotic translation initiation factor 2 subunit gamma X |
| Peak binding time (min) | 51.5 |
| Cluster | III |
| Cluster membership (corr) | 0.996 |
| Peak broadness (1 / std of log2 intensities) | 1.32 |
| Cluster expected from GO | VI |
| Subcellular localization (Human Protein Atlas) | |
| Subcellular localization (Human Cell Map) | NMF result: miscellaneous, SAFE result: no prediction |
| RMSE (expected - observed) | 1.17 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of EIF2S3 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| P05198 | EIF2S1 | 98.9 | VI | Cytosol;Nucleoplasm | NMF result: miscellaneous, SAFE result: - | 2 | 4 |
| O95793 | STAU1 | 111.0 | VI | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| Q15717 | ELAVL1 | 46.3 | III | Cytosol;Nucleoli;Nucleus | NMF result: miscellaneous, SAFE result: paraspeckles | 1 | 1 |
| Q8NDD1 | C1orf131 | 57.7 | IV | Cytosol;Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q9BRP8 | PYM1 | 247.2 | VII | Cell Junctions;Cytosol;Nucleoli;Nucleus | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: - | 1 | 1 |
| P53999 | SUB1 | 43.3 | II | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q86VM9 | ZC3H18 | 39.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P08621 | SNRNP70 | 32.2 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q12986 | NFX1 | 77.5 | V | Cytosol;Nucleus | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q9C0B0 | UNK | 88.4 | VI | Cytoplasmic bodies;Cytosol | NMF result: centrosome, SAFE result: centrosome enriched, P-body enriched | 1 | 1 |
| Q15029 | EFTUD2 | 45.5 | III | Cytosol;Nucleoplasm | NMF result: miscellaneous, SAFE result: spliceosomal complex I | 1 | 1 |
| Q13148 | TARDBP | 49.3 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |